Oxidative behaviour of apomorphine and its metabolites
The metabolism of apomorphine is quite complex due to interactions with proteins and other tissue components that affect its pharmacokinetic profile. The electrochemical oxidation mechanism of apomorphine and of some synthesised apomorphine derivatives was studied. It was found to be related to the...
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| Veröffentlicht in: | Bioelectrochemistry (Amsterdam, Netherlands) Netherlands), 2002, Vol.55 (1), p.113-114 |
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| container_title | Bioelectrochemistry (Amsterdam, Netherlands) |
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| creator | Garrido, J.M.P.J Delerue-Matos, C Borges, M.F.M Macedo, T.R.A Oliveira-Brett, A.M |
| description | The metabolism of apomorphine is quite complex due to interactions with proteins and other tissue components that affect its pharmacokinetic profile. The electrochemical oxidation mechanism of apomorphine and of some synthesised apomorphine derivatives was studied. It was found to be related to the reaction of
o-diphenol and tertiary amine groups and strongly dependent on pH. |
| doi_str_mv | 10.1016/S1567-5394(01)00169-4 |
| format | Article |
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| ispartof | Bioelectrochemistry (Amsterdam, Netherlands), 2002, Vol.55 (1), p.113-114 |
| issn | 1567-5394 1878-562X |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Apomorphine Apomorphine - chemistry Apomorphine - metabolism Electrochemistry Hydrogen-Ion Concentration Oxidation-Reduction Oxidative behaviour |
| title | Oxidative behaviour of apomorphine and its metabolites |
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