Solid-Phase Total Synthesis of Scytalidamide A
The first total synthesis of the natural cyclic heptapeptide scytalidamide A was achieved on solid phase using two different resins, a phenylalanine silane resin and a 4-methoxybenzaldehyde backbone linker resin. The synthetic product confirms the structure of the natural product reported in the pre...
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| Veröffentlicht in: | Journal of organic chemistry 2003-11, Vol.68 (23), p.8774-8779 |
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| container_end_page | 8779 |
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| container_issue | 23 |
| container_start_page | 8774 |
| container_title | Journal of organic chemistry |
| container_volume | 68 |
| creator | Gu, Wenxin Silverman, Richard B |
| description | The first total synthesis of the natural cyclic heptapeptide scytalidamide A was achieved on solid phase using two different resins, a phenylalanine silane resin and a 4-methoxybenzaldehyde backbone linker resin. The synthetic product confirms the structure of the natural product reported in the preceding paper in this issue (Tan, L. T.; Cheng, X. C.; Jensen, P. R.; Fenical, W. J. Org. Chem. 2003, 68, 8767). |
| doi_str_mv | 10.1021/jo0346712 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0022-3263 |
| ispartof | Journal of organic chemistry, 2003-11, Vol.68 (23), p.8774-8779 |
| issn | 0022-3263 1520-6904 |
| language | eng |
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| source | MEDLINE; American Chemical Society Journals |
| subjects | Chemistry Exact sciences and technology Molecular Structure Nuclear Magnetic Resonance, Biomolecular Organic chemistry Peptides Peptides, Cyclic - chemical synthesis Peptides, Cyclic - chemistry Preparations and properties |
| title | Solid-Phase Total Synthesis of Scytalidamide A |
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