11,12-Epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-α-Induced VCAM-1 expression
A series of 11,12-EET analogues were synthesized and compared using a human endothelial cell based TNF-α-induced VCAM-1 expression assay. The resulting data were used to map a putative recognition/binding domain for 11,12-EET. A series of 11,12-EET analogues were synthesized and compared using a hum...
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Veröffentlicht in: | Bioorganic & medicinal chemistry letters 2003-11, Vol.13 (22), p.4011-4014 |
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Sprache: | eng |
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