Familial Clustering of Intracerebral Hemorrhage: A Prospective Study in North Carolina
Few studies have assessed the frequency of familial clustering in intracerebral hemorrhage (ICH). Of 144 patients with ICH prospectively assessed, 14 (9.8%) had a positive family history of ICH (FH+). Four pedigrees had more than two affected family members. Comparisons between FH+ and FH– probands...
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| Veröffentlicht in: | Neuroepidemiology 2002-01, Vol.21 (1), p.18-21 |
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| creator | Alberts, M.J. McCarron, M.O. Hoffmann, K.L. Graffagnino, C. |
| description | Few studies have assessed the frequency of familial clustering in intracerebral hemorrhage (ICH). Of 144 patients with ICH prospectively assessed, 14 (9.8%) had a positive family history of ICH (FH+). Four pedigrees had more than two affected family members. Comparisons between FH+ and FH– probands demonstrated no significant differences in race, age, sex, ICH type or location. An underlying genetic etiology may account for familial clustering in some ICH patients. |
| doi_str_mv | 10.1159/000048609 |
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Of 144 patients with ICH prospectively assessed, 14 (9.8%) had a positive family history of ICH (FH+). Four pedigrees had more than two affected family members. Comparisons between FH+ and FH– probands demonstrated no significant differences in race, age, sex, ICH type or location. An underlying genetic etiology may account for familial clustering in some ICH patients.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>11744821</pmid><doi>10.1159/000048609</doi><tpages>4</tpages></addata></record> |
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| source | Karger Journals; MEDLINE |
| subjects | Aged Aged, 80 and over Basal Ganglia Cerebrovascular Disease - epidemiology Basal Ganglia Cerebrovascular Disease - genetics Cerebral Hemorrhage - epidemiology Cerebral Hemorrhage - genetics Cluster Analysis Cross-Sectional Studies Female Genetic Predisposition to Disease - genetics Humans Male Middle Aged North Carolina Original Paper Pedigree Prospective Studies Risk Factors |
| title | Familial Clustering of Intracerebral Hemorrhage: A Prospective Study in North Carolina |
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