Chromatid transport by pantographic motors (PMS)
The paper discusses a system of hinged leverages functioning as (vectorial) pantographic motors (PMs). Mediated by ratchets, PMs are suited for ferrying mammalian chromatids to mitotic antipoles. Several self-rectifying modes allow PMs to accurately partition genomes with minimal risk of engendering...
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Veröffentlicht in: | Medical hypotheses 2003-11, Vol.61 (5), p.636-639 |
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description | The paper discusses a system of hinged leverages functioning as (vectorial) pantographic motors (PMs). Mediated by ratchets, PMs are suited for ferrying mammalian chromatids to mitotic antipoles. Several self-rectifying modes allow PMs to accurately partition genomes with minimal risk of engendering aneuploidy. |
doi_str_mv | 10.1016/S0306-9877(03)00254-8 |
format | Article |
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subjects | Aneuploidy Animals Biological Transport, Active Chromatids - metabolism Chromatids - physiology Humans Ions Kinetochores - metabolism Mitosis Models, Theoretical Molecular Motor Proteins |
title | Chromatid transport by pantographic motors (PMS) |
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