Supratentorial primitive neuroectodermal tumours : diffusion-weighted MRI

We report the clinical and pathological findings of supratentorial primitive neuroectodermal tumours (PNETs). These are rare, poorly differentiated, highly malignant neoplasms occurring primarily in young individuals. They frequently show dissemination to the spinal cord and sometimes also beyond ne...

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Veröffentlicht in:Neuroradiology 2000-06, Vol.42 (6), p.393-398
Hauptverfasser: KLISCH, J, HUSSTEDT, H, HENNINGS, S, VELTHOVEN, V. V, PAGENSTECHER, A, SCHUMACHER, M
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Sprache:eng
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Zusammenfassung:We report the clinical and pathological findings of supratentorial primitive neuroectodermal tumours (PNETs). These are rare, poorly differentiated, highly malignant neoplasms occurring primarily in young individuals. They frequently show dissemination to the spinal cord and sometimes also beyond neuraxis. Preoperative radiological diagnosis is difficult, due to the nonspecific CT and MRI characteristics. Our findings indicate that diffusion-weighted imaging (DWI) can be used to show the solid portion of the tumour preoperatively and to monitor postsurgical recovery. We describe the MRI findings in three patients with histologically confirmed supratentorial PNET, focussing on the role of DWI for improving the specificity of radiological diagnosis.
ISSN:0028-3940
1432-1920
DOI:10.1007/s002340000318