Effect of pravastatin on coronary plaque volume

A volumetric analysis by 3-dimensional intravascular ultrasound revealed that lipid-lowering therapy with pravastatin significantly reduced coronary plaque volume. The changes in plaque volume were inversely correlated with the changes in plasma levels of high-density lipoprotein cholesterol but not...

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Veröffentlicht in:	The American journal of cardiology 2003-10, Vol.92 (8), p.975-977
Hauptverfasser:	Ishikawa, Kazutoshi, Tani, Shigemasa, Watanabe, Ikuyoshi, Matsumoto, Michiaki, Furukawa, Kiyotaka, Nomoto, Kazumiki, Nomoto, Kana, Kushiro, Toshio, Nagao, Ken, Kanmatsuse, Katsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Cardiology. Vascular system Cholesterol, HDL - blood Cholesterol, HDL - drug effects Cholesterol, LDL - blood Cholesterol, LDL - drug effects Coronary Artery Disease - blood Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - drug therapy Coronary heart disease Coronary vessels Coronary Vessels - diagnostic imaging Drug therapy Female Heart Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Imaging, Three-Dimensional Male Medical sciences Middle Aged Pravastatin - therapeutic use Treatment Outcome Ultrasonography, Interventional
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Beschreibung
Zusammenfassung:	A volumetric analysis by 3-dimensional intravascular ultrasound revealed that lipid-lowering therapy with pravastatin significantly reduced coronary plaque volume. The changes in plaque volume were inversely correlated with the changes in plasma levels of high-density lipoprotein cholesterol but not with changes in levels of total cholesterol or low-density lipoprotein cholesterol.
ISSN:	0002-9149 1879-1913
DOI:	10.1016/S0002-9149(03)00982-2