A SNPshot: pharmacogenetics and the future of drug therapy

A SNPshot: pharmacogenetics and the future of drug therapy

Pharmacogenetics holds great promise for the optimization of new drug development and the individualization of clinical therapeutics in the 21st century. In this brief review, we trace the historical roots of pharmacogenetics, discuss its rapidly evolving processes and paradigms, and look towards fu...

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Veröffentlicht in:Trends in biotechnology (Regular ed.) 2000-08, Vol.18 (8), p.334-338
Hauptverfasser: Pfost, Dale R, Boyce-Jacino, Michael T, Grant, Denis M
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Drug development
Drug Therapy - trends
General pharmacology
Individualized medicine
Medical sciences
Pharmacogenetics
Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
Pharmacology. Drug treatments
Polymorphism, Single Nucleotide
Single nucleotide polymorphism
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Zusammenfassung:Pharmacogenetics holds great promise for the optimization of new drug development and the individualization of clinical therapeutics in the 21st century. In this brief review, we trace the historical roots of pharmacogenetics, discuss its rapidly evolving processes and paradigms, and look towards future applications of pharmacogenetics in enhancing the efficiency of the drug development pipeline and in improving patient care.
ISSN:0167-7799
1879-3096
DOI:10.1016/S0167-7799(00)01463-3