Synthesis and antitumour activity of new derivatives of flavone-8-acetic acid (FAA). Part 4: Variation of the basic structure

A range of 11 derivatives of flavone-8-acetic acid (FAA) in which the structure has been substantially altered in different ways have been prepared and their anti-tumour activity evaluated in vitro against a panel of human and murine tumour cell lines and in vivo against MAC 15A. The generally poor...

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Veröffentlicht in:	Archiv der Pharmazie (Weinheim) 2000-06, Vol.333 (6), p.181-188
Hauptverfasser:	Aitken, R A, Bibby, M C, Cooper, P A, Double, J A, Laws, A L, Ritchie, R B, Wilson, D W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - chemical synthesis Antineoplastic Agents - pharmacology Flavonoids - chemical synthesis Flavonoids - pharmacology Humans Mice Structure-Activity Relationship Tumor Cells, Cultured
Online-Zugang:	Volltext
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