IVIAT: a novel method to identify microbial genes expressed specifically during human infections

In vivo induced antigen technology (IVIAT) is a novel technology that can quickly and easily identify in vivo induced genes in human infections, without the use of animal models. This technology is expected to facilitate the discovery of new targets for vaccines, antimicrobials and diagnostic strate...

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Veröffentlicht in:	Trends in Microbiology 2000-07, Vol.8 (7), p.336-339
Hauptverfasser:	Handfield, Martin, Brady, L.Jeannine, Progulske-Fox, Ann, Hillman, Jeffrey D
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Bacterial - genetics Antigens, Bacterial - metabolism Bacteria - genetics Bacteria - pathogenicity Bacterial Infections - microbiology Bacterial Infections - pathology Gene Expression Profiling - methods Genes, Bacterial Humans Infection IVET IVIAT Microarray Pathogenesis STM Virulence Virulence - genetics
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Beschreibung
Zusammenfassung:	In vivo induced antigen technology (IVIAT) is a novel technology that can quickly and easily identify in vivo induced genes in human infections, without the use of animal models. This technology is expected to facilitate the discovery of new targets for vaccines, antimicrobials and diagnostic strategies in a wide range of microbial pathogens.
ISSN:	0966-842X 1878-4380
DOI:	10.1016/S0966-842X(00)01775-3