A Study of the Spread Surface of Polymeric Dispersions of Eudragit
The rheology of non-Newtonian fluid systems is complex. Their experimental study is difficult because of the existence of many dependent variables. In the present work, a mathematical equation is proposed to calculate the spread surface from a simple viscosimetric study in a theoretical way. It was...
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| Veröffentlicht in: | Drug development and industrial pharmacy 2000-01, Vol.26 (7), p.797-801 |
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| container_title | Drug development and industrial pharmacy |
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| creator | Lucero, M. J. Garcia-Andreu, J. Roman, F. Leon, M. J. |
| description | The rheology of non-Newtonian fluid systems is complex. Their experimental study is difficult because of the existence of many dependent variables. In the present work, a mathematical equation is proposed to calculate the spread surface from a simple viscosimetric study in a theoretical way. It was determined for multiple parameters. The spread surface has to be marked because of its direct relation to the shear stress; this fact enabled us to connect one variable dependent on the compression deformation with another dependent on the shear deformation. At the same time, the viscoelastic phenomenon can be evidenced by applying this mathematical equation. |
| doi_str_mv | 10.1081/DDC-100101302 |
| format | Article |
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J.</creatorcontrib><creatorcontrib>Garcia-Andreu, J.</creatorcontrib><creatorcontrib>Roman, F.</creatorcontrib><creatorcontrib>Leon, M. J.</creatorcontrib><title>A Study of the Spread Surface of Polymeric Dispersions of Eudragit</title><title>Drug development and industrial pharmacy</title><addtitle>Drug Dev Ind Pharm</addtitle><description>The rheology of non-Newtonian fluid systems is complex. Their experimental study is difficult because of the existence of many dependent variables. In the present work, a mathematical equation is proposed to calculate the spread surface from a simple viscosimetric study in a theoretical way. It was determined for multiple parameters. The spread surface has to be marked because of its direct relation to the shear stress; this fact enabled us to connect one variable dependent on the compression deformation with another dependent on the shear deformation. At the same time, the viscoelastic phenomenon can be evidenced by applying this mathematical equation.</description><subject>Acrylic Resins</subject><subject>Biological and medical sciences</subject><subject>Compression deformation</subject><subject>Eudragit</subject><subject>General pharmacology</subject><subject>Lactose - analogs & derivatives</subject><subject>Medical sciences</subject><subject>Methylcellulose - analogs & derivatives</subject><subject>Models, Theoretical</subject><subject>Oxazines</subject><subject>Pharmacology. Drug treatments</subject><subject>Physicochemical properties. Structure-activity relationships</subject><subject>Polymers</subject><subject>Polymethacrylic Acids</subject><subject>Rheology</subject><subject>Shear deformation</subject><subject>Shear stress</subject><subject>Spread surface</subject><subject>Stress, Mechanical</subject><subject>Viscoelastic fluids</subject><issn>0363-9045</issn><issn>1520-5762</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10ElPwzAQBWALgaAsR64oB8Qt4CWOnSO0bBISSIWzNY3HNCiJi50I9d-TqmU7cLJkf280foQcM3rOqGYXk8k4ZZQyygTlW2TEJKepVDnfJiMqcpEWNJN7ZD_Gt0HxQspdsjckFWeUj8jVZTLtertMvEu6OSbTRUCwybQPDkpc3T75etlgqMpkUsUFhlj5Nq4ernsb4LXqDsmOgzri0eY8IC8318_ju_Th8fZ-fPmQlkKxLi0yaUFhZh3PuZjJTKMsOLVo2UwrtEo5xVwunc2otrkDpoXIC8EtoNWA4oCcrecugn_vMXamqWKJdQ0t-j4axfjqe8UA0zUsg48xoDOLUDUQloZRsyrNDKWZ79IGf7IZ3M8atL_0uqUBnG4AxBJqF6Atq_jjhC6k0APTa1a1zocGPnyorelgWfvwlRH_raD-ROcIdTcvIaB5831oh17_Wf4TOWGW1w</recordid><startdate>20000101</startdate><enddate>20000101</enddate><creator>Lucero, M. 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J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-945da7e4df2623b548e5920ded1b87ed77f71f65fd408d6fa18336932daed8ae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Acrylic Resins</topic><topic>Biological and medical sciences</topic><topic>Compression deformation</topic><topic>Eudragit</topic><topic>General pharmacology</topic><topic>Lactose - analogs & derivatives</topic><topic>Medical sciences</topic><topic>Methylcellulose - analogs & derivatives</topic><topic>Models, Theoretical</topic><topic>Oxazines</topic><topic>Pharmacology. Drug treatments</topic><topic>Physicochemical properties. Structure-activity relationships</topic><topic>Polymers</topic><topic>Polymethacrylic Acids</topic><topic>Rheology</topic><topic>Shear deformation</topic><topic>Shear stress</topic><topic>Spread surface</topic><topic>Stress, Mechanical</topic><topic>Viscoelastic fluids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lucero, M. J.</creatorcontrib><creatorcontrib>Garcia-Andreu, J.</creatorcontrib><creatorcontrib>Roman, F.</creatorcontrib><creatorcontrib>Leon, M. 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| ispartof | Drug development and industrial pharmacy, 2000-01, Vol.26 (7), p.797-801 |
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| language | eng |
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| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Business Source Complete; Taylor & Francis Journals Complete |
| subjects | Acrylic Resins Biological and medical sciences Compression deformation Eudragit General pharmacology Lactose - analogs & derivatives Medical sciences Methylcellulose - analogs & derivatives Models, Theoretical Oxazines Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships Polymers Polymethacrylic Acids Rheology Shear deformation Shear stress Spread surface Stress, Mechanical Viscoelastic fluids |
| title | A Study of the Spread Surface of Polymeric Dispersions of Eudragit |
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