A Study of the Spread Surface of Polymeric Dispersions of Eudragit

The rheology of non-Newtonian fluid systems is complex. Their experimental study is difficult because of the existence of many dependent variables. In the present work, a mathematical equation is proposed to calculate the spread surface from a simple viscosimetric study in a theoretical way. It was...

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Veröffentlicht in:Drug development and industrial pharmacy 2000-01, Vol.26 (7), p.797-801
Hauptverfasser: Lucero, M. J., Garcia-Andreu, J., Roman, F., Leon, M. J.
Format: Artikel
Sprache:eng
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Zusammenfassung:The rheology of non-Newtonian fluid systems is complex. Their experimental study is difficult because of the existence of many dependent variables. In the present work, a mathematical equation is proposed to calculate the spread surface from a simple viscosimetric study in a theoretical way. It was determined for multiple parameters. The spread surface has to be marked because of its direct relation to the shear stress; this fact enabled us to connect one variable dependent on the compression deformation with another dependent on the shear deformation. At the same time, the viscoelastic phenomenon can be evidenced by applying this mathematical equation.
ISSN:0363-9045
1520-5762
DOI:10.1081/DDC-100101302