Portrait of a P-type pump

Portrait of a P-type pump

The first high resolution structure of an ATP-dependent cation pump of the P-type family — the Ca 2+ -ATPase from the sarcoplasmic reticulum of rabbit muscle — has now been determined.

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Veröffentlicht in:Nature Structural Biology 2000-07, Vol.7 (7), p.532-535
1. Verfasser: McIntosh, David B
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Binding Sites
Biochemistry
Biological Microscopy
Biomedical and Life Sciences
Calcium - metabolism
Calcium-Transporting ATPases - chemistry
Calcium-Transporting ATPases - metabolism
Cell Membrane - enzymology
Cell Membrane - metabolism
Crystallography, X-Ray
Cytoplasm - enzymology
Cytoplasm - metabolism
Life Sciences
Membrane Biology
Models, Molecular
news-and-views
Nucleotides - metabolism
Phosphorylation
Protein Structure
Protein Structure, Tertiary
Rabbits
Sarcoplasmic Reticulum - enzymology
Structure-Activity Relationship
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Beschreibung
Zusammenfassung:The first high resolution structure of an ATP-dependent cation pump of the P-type family — the Ca 2+ -ATPase from the sarcoplasmic reticulum of rabbit muscle — has now been determined.
ISSN:1072-8368
1545-9993
2331-365X
1545-9985
DOI:10.1038/76735