IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms
IgA is the most abundant immunoglobulin produced in mammals; most is secreted as a dimer across mucous membranes. This review discusses the different mechanisms of induction of IgA, and its role in protecting mucosal surfaces against pathogenic and non-pathogenic microorganisms.
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| Veröffentlicht in: | Microbes and Infection 2001-10, Vol.3 (12), p.1021-1035 |
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| container_end_page | 1035 |
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| container_issue | 12 |
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| container_title | Microbes and Infection |
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| creator | Macpherson, Andrew J. Hunziker, Lukas McCoy, Kathy Lamarre, Alain |
| description | IgA is the most abundant immunoglobulin produced in mammals; most is secreted as a dimer across mucous membranes. This review discusses the different mechanisms of induction of IgA, and its role in protecting mucosal surfaces against pathogenic and non-pathogenic microorganisms. |
| doi_str_mv | 10.1016/S1286-4579(01)01460-5 |
| format | Article |
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This review discusses the different mechanisms of induction of IgA, and its role in protecting mucosal surfaces against pathogenic and non-pathogenic microorganisms.</description><subject>Analysis of the immune response. Humoral and cellular immunity</subject><subject>Animals</subject><subject>Antibody production</subject><subject>B-Lymphocytes - physiology</subject><subject>bacteria</subject><subject>Bile - immunology</subject><subject>Biological and medical sciences</subject><subject>Fundamental and applied biological sciences. 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| fulltext | fulltext |
| identifier | ISSN: 1286-4579 |
| ispartof | Microbes and Infection, 2001-10, Vol.3 (12), p.1021-1035 |
| issn | 1286-4579 1769-714X |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Analysis of the immune response. Humoral and cellular immunity Animals Antibody production B-Lymphocytes - physiology bacteria Bile - immunology Biological and medical sciences Fundamental and applied biological sciences. Psychology Fundamental immunology Humans IgA Immunobiology Immunoglobulin A, Secretory - biosynthesis Immunoglobulin Class Switching Intestinal Diseases - immunology intestinal mucosa Intestinal Mucosa - immunology Intestines - microbiology Milk - immunology Rotavirus Infections - immunology viruses |
| title | IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms |
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