It's a kar9ochore to capture microtubules

Microtubule orientation to cortical spatial cues is essential for the fidelity of asymmetric cellular processes. A cortical microtubule-capture site, composed of Bim1 and Kar9, has now been identified in yeast. Bim1 is the yeast homologue of EB1, a binding partner of the adenomatous polyposis coli (...

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Veröffentlicht in:	Nature cell biology 2000-06, Vol.2 (6), p.E96-E98
1. Verfasser:	Bloom, Kerry
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding proteins Biomedical and Life Sciences Cancer Research Cell Biology Cell Cycle Proteins - metabolism Conserved Sequence Developmental Biology Fungal Proteins - metabolism Kinetochores Kinetochores - metabolism Life Sciences Microtubule Proteins - metabolism Microtubules Microtubules - metabolism news-and-views Nuclear Proteins - metabolism Physiological aspects Saccharomyces cerevisiae Proteins Stem Cells Yeasts
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Beschreibung
Zusammenfassung:	Microtubule orientation to cortical spatial cues is essential for the fidelity of asymmetric cellular processes. A cortical microtubule-capture site, composed of Bim1 and Kar9, has now been identified in yeast. Bim1 is the yeast homologue of EB1, a binding partner of the adenomatous polyposis coli (APC), indicating that important features of this complex may be highly conserved.
ISSN:	1465-7392 1476-4679
DOI:	10.1038/35014089