Association of chronic congestive heart failure in humans with an intrinsic upregulation in skeletal muscle sarcoplasmic reticulum calcium ion adenosine triphosphatase activity

Association of chronic congestive heart failure in humans with an intrinsic upregulation in skeletal muscle sarcoplasmic reticulum calcium ion adenosine triphosphatase activity

This study examined the maximal calcium ion adenosine triphosphatase activity of the sarcoplasmic reticulum in skeletal muscle in 18 men and 6 women with chronic congestive heart failure (average left ventricular ejection fraction 24 +/- 2%, mean +/- SE). Eight men and 9 women served as age-matched...

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Veröffentlicht in:The American journal of cardiology 2000-06, Vol.85 (12), p.1498-1500
Hauptverfasser: Green, Howard J., Duscha, Brian D., Kraus, William E., Keteyian, Steve J., Sullivan, Marty J.
Format: Artikel
Sprache:eng
Schlagworte:
Adenosine Triphosphate - metabolism
Biological and medical sciences
Calcium
Calcium - metabolism
Cardiology. Vascular system
Case-Control Studies
Chronic Disease
Female
Heart
Heart failure
Heart Failure - metabolism
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Humans
Male
Medical sciences
Muscle, Skeletal - metabolism
Muscular system
Sarcoplasmic Reticulum - metabolism
Up-Regulation
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Zusammenfassung:This study examined the maximal calcium ion adenosine triphosphatase activity of the sarcoplasmic reticulum in skeletal muscle in 18 men and 6 women with chronic congestive heart failure (average left ventricular ejection fraction 24 +/- 2%, mean +/- SE). Eight men and 9 women served as age-matched healthy controls.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(00)00804-3