Retrospective Studies of Penicillin-resistant Pneumococcal Acute Otitis Media in Infants and Children: Epidemiological Study

Retrospective studies of the prognostic factors of infantile acute otitis media caused by Penicillinresistant Streptococcus pneumoniae were performed. In this study, the following items were discussed the following items; age, sex, presence of nurturance, presence of acute otitis media, presence of sibling, presence of past antibiotic therapy, presence of past therapy for this type of otitis media, MIC of PCG, MIC of CDTR. 1. Statistically significant results were obtained in the following items; age, presence of acute otitis media, presence of past antibiotic therapy, presence of past therapy of this type of otitis media (especially that treated by an otolaryngologist). 2. In previous reports, persistent and recurrent otitis media was influenced by participation in kindergarten groups. However in this study, a statistically significant difference was not recognized. 3. Statistically significant results were not recognized in the MIC of PCG and the MIC of CDTR for PRSP. 4. In this study, immunities of each infants were not discussed, but it was necessary for us to examine the factors of immunity in infants, such as specific pneumococcal antigen and type-specific IgG2 antibody and comparison of such titers to the various results of treatment.