A statistical analysis of nucleotide substitutions in the Drosophila Adh region reflects irregularities in molecular clocks
Substitutions rates are expected to be rather constant when a gene is compared between species. To analyze this feature, Ka / Ks ratios have been studied for Alcohol dehydrogenase (Adh) and Alcolpol dehydrogenase duplication (Adh-dup) genes in Drosophila species. Adh Ka/Ks values are lower in intras...
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| Veröffentlicht in: | Genes & Genetic Systems 2001, Vol.76(3), pp.209-212 |
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| creator | Albalat, R. (Universitat de Barcelona (Spain)) Arenas, C Mestres, F |
| description | Substitutions rates are expected to be rather constant when a gene is compared between species. To analyze this feature, Ka / Ks ratios have been studied for Alcohol dehydrogenase (Adh) and Alcolpol dehydrogenase duplication (Adh-dup) genes in Drosophila species. Adh Ka/Ks values are lower in intrasubgenus comparisons involving species of the Sophophora group than when these species are compared to the D. immigrans and S. lebanonensis, and this difference does not occur in the Adhdup comparisons. |
| doi_str_mv | 10.1266/ggs.76.209 |
| format | Article |
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| ispartof | Genes & Genetic Systems, 2001, Vol.76(3), pp.209-212 |
| issn | 1341-7568 1880-5779 |
| language | eng |
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| source | J-STAGE Free; MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adh gene ALCOHOL DEHYDROGENASE Alcohol Dehydrogenase - genetics Animals Base Composition DNA - chemistry DNA - genetics DROSOPHILA Drosophila - enzymology Drosophila - genetics Drosophila immigrans dup gene EVOLUTION Evolution, Molecular Gene Duplication GENES Genes, Insect Sophophora lebanonensis Species Specificity Time Factors |
| title | A statistical analysis of nucleotide substitutions in the Drosophila Adh region reflects irregularities in molecular clocks |
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