A statistical analysis of nucleotide substitutions in the Drosophila Adh region reflects irregularities in molecular clocks

A statistical analysis of nucleotide substitutions in the Drosophila Adh region reflects irregularities in molecular clocks

Substitutions rates are expected to be rather constant when a gene is compared between species. To analyze this feature, Ka / Ks ratios have been studied for Alcohol dehydrogenase (Adh) and Alcolpol dehydrogenase duplication (Adh-dup) genes in Drosophila species. Adh Ka/Ks values are lower in intras...

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Veröffentlicht in:Genes & Genetic Systems 2001, Vol.76(3), pp.209-212
Hauptverfasser: Albalat, R. (Universitat de Barcelona (Spain)), Arenas, C, Mestres, F
Format: Artikel
Sprache:eng
Schlagworte:
Adh gene
ALCOHOL DEHYDROGENASE
Alcohol Dehydrogenase - genetics
Animals
Base Composition
DNA - chemistry
DNA - genetics
DROSOPHILA
Drosophila - enzymology
Drosophila - genetics
Drosophila immigrans
dup gene
EVOLUTION
Evolution, Molecular
Gene Duplication
GENES
Genes, Insect
Sophophora lebanonensis
Species Specificity
Time Factors
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Beschreibung
Zusammenfassung:Substitutions rates are expected to be rather constant when a gene is compared between species. To analyze this feature, Ka / Ks ratios have been studied for Alcohol dehydrogenase (Adh) and Alcolpol dehydrogenase duplication (Adh-dup) genes in Drosophila species. Adh Ka/Ks values are lower in intrasubgenus comparisons involving species of the Sophophora group than when these species are compared to the D. immigrans and S. lebanonensis, and this difference does not occur in the Adhdup comparisons.
ISSN:1341-7568
1880-5779
DOI:10.1266/ggs.76.209