Salivary Cytomegalovirus (CMV) Shedding, Glycoprotein B Genotype Distribution, and CMV Disease in Human Immunodeficiency Virus-Seropositive Patients

To assess the frequency of shedding of cytomegalovirus (CMV) in saliva, the distribution of CMV glycoprotein B (gB) genotypes, and the occurrence of CMV diseases, we screened 98 human immunodeficiency virus (HIV)-seropositive patients without CMV disease. CMV was detected by culture more frequently...

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Veröffentlicht in:	Clinical infectious diseases 2001-10, Vol.33 (8), p.1406-1411
Hauptverfasser:	Fidouh-Houhou, N., Duval, X., Bissuel, F., Bourbonneux, V., Flandre, P., Ecobichon, J. L., Jordan, M. C., Vildé, J. L., Brun-Vézinet, F., Leport, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS AIDS-Related Opportunistic Infections - virology Biological and medical sciences Blood Cytomegalovirus Cytomegalovirus - genetics Cytomegalovirus - isolation & purification Cytomegalovirus - physiology Cytomegalovirus Infections - blood Cytomegalovirus Infections - virology Female Genotypes Glycoproteins HIV HIV Infections - virology HIV/AIDS Human viral diseases Humans Infections Infectious diseases Male Medical sciences Retinitis Saliva Saliva - virology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Envelope Proteins - genetics Viremia Viremia - virology Virus Cultivation Virus Shedding
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Zusammenfassung:	To assess the frequency of shedding of cytomegalovirus (CMV) in saliva, the distribution of CMV glycoprotein B (gB) genotypes, and the occurrence of CMV diseases, we screened 98 human immunodeficiency virus (HIV)-seropositive patients without CMV disease. CMV was detected by culture more frequently in saliva (45 [46%] of 98 patients) than in blood (7 [7.5%] of 93) and was associated with CD4 cell counts
ISSN:	1058-4838 1537-6591
DOI:	10.1086/322630