Inflammatory cytokines and antigen-responsive mononuclear cells in peripheral blood of cattle infected with Salmonella takoradi

To determine the immunological response in lactating dairy cows infected with Salmonella (S.) Takoradi, the relationships among distributions of peripheral blood mononuclear cell (PBMC) subpopulations, endotoxin concentrations and dynamics of inflammatory cytokines in blood were investigated. The ra...

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Veröffentlicht in:	Journal of veterinary medical science 2001-08, Vol.63 (8), p.860-865
Hauptverfasser:	Konna, S, Ohtsuka, H, Sakamoto, T, Nakaoka, Y, Kiku, Y, Fukuda, S, Koiwa, M, Takahashi, J, Taniyama, H, Yokomizo, Y, Okada, H, Yoshino, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Assay Cattle Cattle Diseases - immunology Cattle Diseases - microbiology CD4-CD8 Ratio - veterinary Cells, Cultured Cytokines - biosynthesis Cytokines - blood Endotoxemia - blood Endotoxemia - immunology Endotoxemia - veterinary Enzyme-Linked Immunosorbent Assay - veterinary Female Flow Cytometry - veterinary Humans Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - microbiology Salmonella - growth & development Salmonella - immunology Salmonella Infections, Animal - blood Salmonella Infections, Animal - immunology
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Zusammenfassung:	To determine the immunological response in lactating dairy cows infected with Salmonella (S.) Takoradi, the relationships among distributions of peripheral blood mononuclear cell (PBMC) subpopulations, endotoxin concentrations and dynamics of inflammatory cytokines in blood were investigated. The ratio of CD4+ T cells to CD8+ T cells was significantly lower in the affected cattle than in the control cattle (p
ISSN:	0916-7250