Antidiabetic Activity of the Rhizoma of Anemarrhena asphodeloides and Active Components, Mangiferin and Its Glucoside

The antidiabetic activity of the rhizoma of Anemarrhena asphodeloides was investigated in KK-Ay mice, an animal model of genetic type 2 diabetes. The water extract of the rhizoma (AA) (90 mg/kg) reduced blood glucose levels from 570±29 to 401±59 mg/dl 7 h after oral administration (p

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biological & pharmaceutical bulletin 2001, Vol.24(9), pp.1009-1011
Hauptverfasser:	MIURA, Toshihiro, ICHIKI, Hiroyuki, IWAMOTO, Naoki, KATO, Motoshi, KUBO, Masayoshi, SASAKI, Hiroshi, OKADA, Minoru, ISHIDA, Torao, SEINO, Yutaka, TANIGAWA, Keiichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemarrhena asphodeloides Animals antidiabetic activity Biological and medical sciences Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - genetics Dose-Response Relationship, Drug General pharmacology Glucose Tolerance Test Glucosides - pharmacology Hypoglycemic Agents - therapeutic use KK-Ay mouse mangiferin Medical sciences Mice Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - pharmacology Plants, Medicinal - chemistry Tolbutamide - pharmacology Xanthenes - pharmacology Xanthones
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The antidiabetic activity of the rhizoma of Anemarrhena asphodeloides was investigated in KK-Ay mice, an animal model of genetic type 2 diabetes. The water extract of the rhizoma (AA) (90 mg/kg) reduced blood glucose levels from 570±29 to 401±59 mg/dl 7 h after oral administration (p
ISSN:	0918-6158 1347-5215
DOI:	10.1248/bpb.24.1009