Synthesis of Isoquinolines and Naphthyridines by Electrophilic Ring Closure of Iminoalkynes

Synthesis of Isoquinolines and Naphthyridines by Electrophilic Ring Closure of Iminoalkynes

Substituted isoquinolines and naphthyridines have been prepared in good to excellent yields by the reaction of iminoalkynes with a variety of electrophiles under mild reaction conditions.

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Veröffentlicht in:Organic letters 2001-09, Vol.3 (19), p.2973-2976
Hauptverfasser: Huang, Qinhua, Hunter, Jack A, Larock, Richard C
Format: Artikel
Sprache:eng
Schlagworte:
Biological Factors - chemical synthesis
Imines - chemistry
Isoquinolines - chemical synthesis
Naphthyridines - chemical synthesis
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Beschreibung
Zusammenfassung:Substituted isoquinolines and naphthyridines have been prepared in good to excellent yields by the reaction of iminoalkynes with a variety of electrophiles under mild reaction conditions.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol010136h