Human Parvovirus B19 in Cord Blood of Premature Infants

ABSTRACT We investigated whether intrauterine parvovirus B19 infection is associated with premature birth by evaluating parvovirus B19 antibodies and DNA in umbilical cord blood from 76 premature infants. We performed enzyme-linked immunoadsorbent (ELISA) and polymerase chain reaction (PCR) assays t...

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Veröffentlicht in:	American journal of perinatology 2001-08, Vol.18 (5), p.237-240
Hauptverfasser:	Koga, Mayumi, Matsuoka, Takashi, Katayama, Kumiko, Takeda, Kanae, Nakata, Masahiko, Sase, Masakatsu, Kato, Hiroshi, Furukawa, Susumu
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Viral - blood Biological and medical sciences Diseases of mother, fetus and pregnancy DNA, Viral - blood Enzyme-Linked Immunosorbent Assay Female Fetal Blood - immunology Fetal Blood - virology Fetal Diseases - virology Gestational Age Gynecology. Andrology. Obstetrics Humans Immunoglobulin A - blood Immunoglobulin M - blood Infant, Newborn Infant, Premature Medical sciences Obstetric Labor, Premature - etiology ORIGINAL ARTICLES Parvoviridae Infections - complications Parvoviridae Infections - virology Parvovirus B19, Human - immunology Parvovirus B19, Human - isolation & purification Polymerase Chain Reaction Pregnancy Pregnancy. Fetus. Placenta
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Zusammenfassung:	ABSTRACT We investigated whether intrauterine parvovirus B19 infection is associated with premature birth by evaluating parvovirus B19 antibodies and DNA in umbilical cord blood from 76 premature infants. We performed enzyme-linked immunoadsorbent (ELISA) and polymerase chain reaction (PCR) assays to detect B19-specific IgM antibodies and parvovirus DNA. No parvovirus DNA was detected in cord blood sera, and no sample was positive for anti-parvovirus B19 IgM antibodies. Parvovirus appears unlikely to lead to premature birth.
ISSN:	0735-1631 1098-8785
DOI:	10.1055/s-2001-16988