Role of sex hormones in development of pituitary adenoma

Role of sex hormones in development of pituitary adenoma

Role of sex hormones in the development of pituitary adenomas was investigated by analyzing the content of nuclear estradiol and testosterone receptors in different tumors of the anterior pituitary: prolactinomas, meningiomas, growth hormone-producing adenomas, astrocytomas, neurinomas, and ependymo...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2001-04, Vol.131 (4), p.309-311
Hauptverfasser: Babichev, V N, Marova, E I, Kuznetsova, T A, Adamskaya, E I, Shishkina, I V, Y u Kasumova, S
Format: Artikel
Sprache:eng
Schlagworte:
Adenoma - metabolism
Female
Gonadal Steroid Hormones - metabolism
Humans
Male
Pituitary Neoplasms - metabolism
Prolactinoma - metabolism
Receptors, Androgen - metabolism
Receptors, Estradiol - metabolism
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Zusammenfassung:Role of sex hormones in the development of pituitary adenomas was investigated by analyzing the content of nuclear estradiol and testosterone receptors in different tumors of the anterior pituitary: prolactinomas, meningiomas, growth hormone-producing adenomas, astrocytomas, neurinomas, and ependymomas. The concentration of nuclear estrogen and androgen receptors in prolactin-secreting pituitary adenomas was much higher than in growth hormone-producing adenomas and other pituitary tumors.
ISSN:0007-4888
1573-8221
DOI:10.1023/A:1017975313365