Pulsed field gel electrophoresis typing of coagulase-negative staphylococci with decreased susceptibility to teicoplanin isolated from an intensive care unit
Increased isolation of coagulase-negative staphylococci (CoNS) with decreased susceptibility to teicoplanin prompted this epidemiological survey in the authors intensive care unit. Of 224 medical and surgical patients with hepatobiliary disease, in hospital between December 1998 and July 1999, 14 (6...
Gespeichert in:
| Veröffentlicht in: | The Journal of hospital infection 2001-09, Vol.49 (1), p.62-68 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 68 |
|---|---|
| container_issue | 1 |
| container_start_page | 62 |
| container_title | The Journal of hospital infection |
| container_volume | 49 |
| creator | Schlegel, L. Saliba, F. Mangeney, N. Mathieu, D. |
| description | Increased isolation of coagulase-negative staphylococci (CoNS) with decreased susceptibility to teicoplanin prompted this epidemiological survey in the authors intensive care unit. Of 224 medical and surgical patients with hepatobiliary disease, in hospital between December 1998 and July 1999, 14 (6.3%) had at least one isolate of CoNS with decreased susceptibility to teicoplanin. A total of 27 isolates with decreased susceptibility to teicoplanin were recovered from these 14 patients. Pulsed field electrophoresis (PFGE) with Sma I endonuclease demonstrated that CoNS isolates obtained from different patients were unrelated. In addition, different isolates obtain from the same patient were also unrelated, with the exception of two patients. Eighteen out of 27 isolates (66.7%) with decreased susceptibility to teicoplanin were recovered after an earlier treatment with teicoplanin or vancomycin (median 13.1g, range 2.4–32.7g per patient). Only four CoNS strains with decreased susceptibility to teicoplanin induced serious infection, all of which responded well to vancomycin therapy.
Emergence of CoNS strains with decreased susceptibility to teicoplanin remained limited in hospitalized patients, and was not related to a clonal spread of a particular resistant strain. |
| doi_str_mv | 10.1053/jhin.2001.1046 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71150759</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0195670101910461</els_id><sourcerecordid>71150759</sourcerecordid><originalsourceid>FETCH-LOGICAL-c400t-477ecc9d1e85ea4d6bc846f142a3be1327deb0329a2bb179021c2b7c4009ce0d3</originalsourceid><addsrcrecordid>eNqFkT2P1DAQhi0E4paDlhK5QHRZbCfZJCU68XHSSVBAbTnjye6cvHawnTvtj-G_4mhXggZRWbaeef1qHsZeS7GVoq3f3x_Ib5UQslyb3RO2kW2tKjXUw1O2EXJoq10n5BV7kdK9EKK8t8_ZlZSt3Ml-2LBf3xaX0PKJ0Fm-R8fRIeQY5kOImCjxfJrJ73mYOASzX5xJWHncm0wPyFM28-HkAgQA4o-UD9wiRDRrZloS4JxpJEf5xHPgGQnC7IwnzykFZ_L6dQxHbsqDz-jTmgomIl885Zfs2WRKv1eX85r9-PTx-82X6u7r59ubD3cVNELkquk6BBisxL5F09jdCH2zm2SjTD2irFVncRS1GowaR9kNQklQY7cOD4DC1tfs3Tl3juHnginrI5XurjTFsCTdlYWJrh3-C8pe9X1f9wXcnkGIIaWIk54jHU08aSn0ak6v5vRqTq_mysCbS_IyHtH-wS-qCvD2ApgExk3ReKD0Fyc7JWTB-jOGZV8PhFEnIPSAlmIRq22gf1X4DXYvuR0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>18288838</pqid></control><display><type>article</type><title>Pulsed field gel electrophoresis typing of coagulase-negative staphylococci with decreased susceptibility to teicoplanin isolated from an intensive care unit</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Schlegel, L. ; Saliba, F. ; Mangeney, N. ; Mathieu, D.</creator><creatorcontrib>Schlegel, L. ; Saliba, F. ; Mangeney, N. ; Mathieu, D.</creatorcontrib><description>Increased isolation of coagulase-negative staphylococci (CoNS) with decreased susceptibility to teicoplanin prompted this epidemiological survey in the authors intensive care unit. Of 224 medical and surgical patients with hepatobiliary disease, in hospital between December 1998 and July 1999, 14 (6.3%) had at least one isolate of CoNS with decreased susceptibility to teicoplanin. A total of 27 isolates with decreased susceptibility to teicoplanin were recovered from these 14 patients. Pulsed field electrophoresis (PFGE) with Sma I endonuclease demonstrated that CoNS isolates obtained from different patients were unrelated. In addition, different isolates obtain from the same patient were also unrelated, with the exception of two patients. Eighteen out of 27 isolates (66.7%) with decreased susceptibility to teicoplanin were recovered after an earlier treatment with teicoplanin or vancomycin (median 13.1g, range 2.4–32.7g per patient). Only four CoNS strains with decreased susceptibility to teicoplanin induced serious infection, all of which responded well to vancomycin therapy.
Emergence of CoNS strains with decreased susceptibility to teicoplanin remained limited in hospitalized patients, and was not related to a clonal spread of a particular resistant strain.</description><identifier>ISSN: 0195-6701</identifier><identifier>EISSN: 1532-2939</identifier><identifier>DOI: 10.1053/jhin.2001.1046</identifier><identifier>PMID: 11516189</identifier><language>eng</language><publisher>Kent: Elsevier Ltd</publisher><subject>Adult ; Aged ; Anti-Bacterial Agents - pharmacology ; Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Biological and medical sciences ; Coagulase-negative staphylococci ; Drug Resistance, Microbial ; Electrophoresis, Gel, Pulsed-Field ; Female ; France - epidemiology ; Humans ; Intensive Care Units ; Liver Failure - etiology ; Liver Failure - microbiology ; Liver Transplantation ; Male ; Medical sciences ; Middle Aged ; PFGE ; Pharmacology. Drug treatments ; Postoperative Complications - microbiology ; Prospective Studies ; Staphylococcal Infections - drug therapy ; Staphylococcal Infections - epidemiology ; Staphylococcal Infections - microbiology ; Staphylococcus ; Staphylococcus - classification ; Staphylococcus - drug effects ; Staphylococcus - isolation & purification ; Teicoplanin - pharmacology ; teicoplanin resistance</subject><ispartof>The Journal of hospital infection, 2001-09, Vol.49 (1), p.62-68</ispartof><rights>2001 The Hospital Infection Society</rights><rights>2001 INIST-CNRS</rights><rights>Copyright 2001 The Hospital Infection Society.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-477ecc9d1e85ea4d6bc846f142a3be1327deb0329a2bb179021c2b7c4009ce0d3</citedby><cites>FETCH-LOGICAL-c400t-477ecc9d1e85ea4d6bc846f142a3be1327deb0329a2bb179021c2b7c4009ce0d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0195670101910461$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1117201$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11516189$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schlegel, L.</creatorcontrib><creatorcontrib>Saliba, F.</creatorcontrib><creatorcontrib>Mangeney, N.</creatorcontrib><creatorcontrib>Mathieu, D.</creatorcontrib><title>Pulsed field gel electrophoresis typing of coagulase-negative staphylococci with decreased susceptibility to teicoplanin isolated from an intensive care unit</title><title>The Journal of hospital infection</title><addtitle>J Hosp Infect</addtitle><description>Increased isolation of coagulase-negative staphylococci (CoNS) with decreased susceptibility to teicoplanin prompted this epidemiological survey in the authors intensive care unit. Of 224 medical and surgical patients with hepatobiliary disease, in hospital between December 1998 and July 1999, 14 (6.3%) had at least one isolate of CoNS with decreased susceptibility to teicoplanin. A total of 27 isolates with decreased susceptibility to teicoplanin were recovered from these 14 patients. Pulsed field electrophoresis (PFGE) with Sma I endonuclease demonstrated that CoNS isolates obtained from different patients were unrelated. In addition, different isolates obtain from the same patient were also unrelated, with the exception of two patients. Eighteen out of 27 isolates (66.7%) with decreased susceptibility to teicoplanin were recovered after an earlier treatment with teicoplanin or vancomycin (median 13.1g, range 2.4–32.7g per patient). Only four CoNS strains with decreased susceptibility to teicoplanin induced serious infection, all of which responded well to vancomycin therapy.
Emergence of CoNS strains with decreased susceptibility to teicoplanin remained limited in hospitalized patients, and was not related to a clonal spread of a particular resistant strain.</description><subject>Adult</subject><subject>Aged</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Biological and medical sciences</subject><subject>Coagulase-negative staphylococci</subject><subject>Drug Resistance, Microbial</subject><subject>Electrophoresis, Gel, Pulsed-Field</subject><subject>Female</subject><subject>France - epidemiology</subject><subject>Humans</subject><subject>Intensive Care Units</subject><subject>Liver Failure - etiology</subject><subject>Liver Failure - microbiology</subject><subject>Liver Transplantation</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>PFGE</subject><subject>Pharmacology. Drug treatments</subject><subject>Postoperative Complications - microbiology</subject><subject>Prospective Studies</subject><subject>Staphylococcal Infections - drug therapy</subject><subject>Staphylococcal Infections - epidemiology</subject><subject>Staphylococcal Infections - microbiology</subject><subject>Staphylococcus</subject><subject>Staphylococcus - classification</subject><subject>Staphylococcus - drug effects</subject><subject>Staphylococcus - isolation & purification</subject><subject>Teicoplanin - pharmacology</subject><subject>teicoplanin resistance</subject><issn>0195-6701</issn><issn>1532-2939</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkT2P1DAQhi0E4paDlhK5QHRZbCfZJCU68XHSSVBAbTnjye6cvHawnTvtj-G_4mhXggZRWbaeef1qHsZeS7GVoq3f3x_Ib5UQslyb3RO2kW2tKjXUw1O2EXJoq10n5BV7kdK9EKK8t8_ZlZSt3Ml-2LBf3xaX0PKJ0Fm-R8fRIeQY5kOImCjxfJrJ73mYOASzX5xJWHncm0wPyFM28-HkAgQA4o-UD9wiRDRrZloS4JxpJEf5xHPgGQnC7IwnzykFZ_L6dQxHbsqDz-jTmgomIl885Zfs2WRKv1eX85r9-PTx-82X6u7r59ubD3cVNELkquk6BBisxL5F09jdCH2zm2SjTD2irFVncRS1GowaR9kNQklQY7cOD4DC1tfs3Tl3juHnginrI5XurjTFsCTdlYWJrh3-C8pe9X1f9wXcnkGIIaWIk54jHU08aSn0ak6v5vRqTq_mysCbS_IyHtH-wS-qCvD2ApgExk3ReKD0Fyc7JWTB-jOGZV8PhFEnIPSAlmIRq22gf1X4DXYvuR0</recordid><startdate>20010901</startdate><enddate>20010901</enddate><creator>Schlegel, L.</creator><creator>Saliba, F.</creator><creator>Mangeney, N.</creator><creator>Mathieu, D.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>20010901</creationdate><title>Pulsed field gel electrophoresis typing of coagulase-negative staphylococci with decreased susceptibility to teicoplanin isolated from an intensive care unit</title><author>Schlegel, L. ; Saliba, F. ; Mangeney, N. ; Mathieu, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-477ecc9d1e85ea4d6bc846f142a3be1327deb0329a2bb179021c2b7c4009ce0d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Antibacterial agents</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Biological and medical sciences</topic><topic>Coagulase-negative staphylococci</topic><topic>Drug Resistance, Microbial</topic><topic>Electrophoresis, Gel, Pulsed-Field</topic><topic>Female</topic><topic>France - epidemiology</topic><topic>Humans</topic><topic>Intensive Care Units</topic><topic>Liver Failure - etiology</topic><topic>Liver Failure - microbiology</topic><topic>Liver Transplantation</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>PFGE</topic><topic>Pharmacology. Drug treatments</topic><topic>Postoperative Complications - microbiology</topic><topic>Prospective Studies</topic><topic>Staphylococcal Infections - drug therapy</topic><topic>Staphylococcal Infections - epidemiology</topic><topic>Staphylococcal Infections - microbiology</topic><topic>Staphylococcus</topic><topic>Staphylococcus - classification</topic><topic>Staphylococcus - drug effects</topic><topic>Staphylococcus - isolation & purification</topic><topic>Teicoplanin - pharmacology</topic><topic>teicoplanin resistance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schlegel, L.</creatorcontrib><creatorcontrib>Saliba, F.</creatorcontrib><creatorcontrib>Mangeney, N.</creatorcontrib><creatorcontrib>Mathieu, D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of hospital infection</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schlegel, L.</au><au>Saliba, F.</au><au>Mangeney, N.</au><au>Mathieu, D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulsed field gel electrophoresis typing of coagulase-negative staphylococci with decreased susceptibility to teicoplanin isolated from an intensive care unit</atitle><jtitle>The Journal of hospital infection</jtitle><addtitle>J Hosp Infect</addtitle><date>2001-09-01</date><risdate>2001</risdate><volume>49</volume><issue>1</issue><spage>62</spage><epage>68</epage><pages>62-68</pages><issn>0195-6701</issn><eissn>1532-2939</eissn><abstract>Increased isolation of coagulase-negative staphylococci (CoNS) with decreased susceptibility to teicoplanin prompted this epidemiological survey in the authors intensive care unit. Of 224 medical and surgical patients with hepatobiliary disease, in hospital between December 1998 and July 1999, 14 (6.3%) had at least one isolate of CoNS with decreased susceptibility to teicoplanin. A total of 27 isolates with decreased susceptibility to teicoplanin were recovered from these 14 patients. Pulsed field electrophoresis (PFGE) with Sma I endonuclease demonstrated that CoNS isolates obtained from different patients were unrelated. In addition, different isolates obtain from the same patient were also unrelated, with the exception of two patients. Eighteen out of 27 isolates (66.7%) with decreased susceptibility to teicoplanin were recovered after an earlier treatment with teicoplanin or vancomycin (median 13.1g, range 2.4–32.7g per patient). Only four CoNS strains with decreased susceptibility to teicoplanin induced serious infection, all of which responded well to vancomycin therapy.
Emergence of CoNS strains with decreased susceptibility to teicoplanin remained limited in hospitalized patients, and was not related to a clonal spread of a particular resistant strain.</abstract><cop>Kent</cop><pub>Elsevier Ltd</pub><pmid>11516189</pmid><doi>10.1053/jhin.2001.1046</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0195-6701 |
| ispartof | The Journal of hospital infection, 2001-09, Vol.49 (1), p.62-68 |
| issn | 0195-6701 1532-2939 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71150759 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adult Aged Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Coagulase-negative staphylococci Drug Resistance, Microbial Electrophoresis, Gel, Pulsed-Field Female France - epidemiology Humans Intensive Care Units Liver Failure - etiology Liver Failure - microbiology Liver Transplantation Male Medical sciences Middle Aged PFGE Pharmacology. Drug treatments Postoperative Complications - microbiology Prospective Studies Staphylococcal Infections - drug therapy Staphylococcal Infections - epidemiology Staphylococcal Infections - microbiology Staphylococcus Staphylococcus - classification Staphylococcus - drug effects Staphylococcus - isolation & purification Teicoplanin - pharmacology teicoplanin resistance |
| title | Pulsed field gel electrophoresis typing of coagulase-negative staphylococci with decreased susceptibility to teicoplanin isolated from an intensive care unit |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T20%3A16%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pulsed%20field%20gel%20electrophoresis%20typing%20of%20coagulase-negative%20staphylococci%20with%20decreased%20susceptibility%20to%20teicoplanin%20isolated%20from%20an%20intensive%20care%20unit&rft.jtitle=The%20Journal%20of%20hospital%20infection&rft.au=Schlegel,%20L.&rft.date=2001-09-01&rft.volume=49&rft.issue=1&rft.spage=62&rft.epage=68&rft.pages=62-68&rft.issn=0195-6701&rft.eissn=1532-2939&rft_id=info:doi/10.1053/jhin.2001.1046&rft_dat=%3Cproquest_cross%3E71150759%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=18288838&rft_id=info:pmid/11516189&rft_els_id=S0195670101910461&rfr_iscdi=true |