Lymphocyte development from hematopoietic stem cells

The recent application of new techniques, such as multi-color cell sorting and the production of transgenic and gene-knockout mice, has contributed to a better understanding of lymphocyte development from hematopoietic stem cells. Now that we can purify progenitors at different maturational stages d...

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Veröffentlicht in:	Current Opinion in Genetics & Development 2001-10, Vol.11 (5), p.520-526
Hauptverfasser:	Kondo, Motonari, Scherer, David C, King, Angela G, Manz, Markus G, Weissman, Irving L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Cell Lineage commitment cytokine receptor Dendritic Cells - cytology Gene Rearrangement - genetics hematopoietic stem cell Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - metabolism Humans Killer Cells, Natural - cytology Lymphocytes - cytology Lymphocytes - metabolism lymphopoiesis Receptors, Antigen - genetics Receptors, Cytokine - metabolism Signal Transduction transcription factor Transcription Factors - metabolism
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