Low-dose dexamethasone augments the ovarian response to exogenous gonadotrophins leading to a reduction in cycle cancellation rate in a standard IVF programme

BACKGROUND: Cancellation of assisted conception cycles because of poor ovarian response to gonadotrophins is a significant problem in assisted reproduction. Various adjuvant treatments have been suggested to improve responsiveness. This study reports on the potential benefits of low dose dexamethaso...

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Veröffentlicht in:	Human reproduction (Oxford) 2001-09, Vol.16 (9), p.1861-1865
Hauptverfasser:	Keay, S.D., Lenton, E.A., Cooke, I.D., Hull, M.G.R., Jenkins, J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Birth control Dexamethasone - administration & dosage Dexamethasone - therapeutic use dexamethasone co-treatment Dose-Response Relationship, Drug Embryo Implantation Female Fertilization in Vitro Glucocorticoids - administration & dosage Glucocorticoids - therapeutic use gonadotrophins Gonadotropins - therapeutic use Gynecology. Andrology. Obstetrics Humans IVF Medical sciences ovarian stimulation Ovary - drug effects Ovulation Induction - methods Polycystic Ovary Syndrome - physiopathology poor response Pregnancy Pregnancy Rate Sterility. Assisted procreation Treatment Outcome
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Zusammenfassung:	BACKGROUND: Cancellation of assisted conception cycles because of poor ovarian response to gonadotrophins is a significant problem in assisted reproduction. Various adjuvant treatments have been suggested to improve responsiveness. This study reports on the potential benefits of low dose dexamethasone. METHODS: Patients
ISSN:	0268-1161 1460-2350
DOI:	10.1093/humrep/16.9.1861