Minireview: mechanisms by which the metabolic syndrome and diabetes impair memory

Minireview: mechanisms by which the metabolic syndrome and diabetes impair memory

Type 2 diabetes is associated with an increased risk of cognitive dysfunction. These effects seem particularly true for memory functions. This article examines how diabetes and the biological changes that occur with diabetes such as hyperglycemia, changes in insulin concentration, hypertension, and...

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Veröffentlicht in:The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2000-05, Vol.55 (5), p.B228-B232
Hauptverfasser: Kumari, M, Brunner, E, Fuhrer, R
Format: Artikel
Sprache:eng
Schlagworte:
Cognition & reasoning
Dementia - etiology
Diabetes
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - metabolism
Humans
Hyperglycemia - complications
Hyperinsulinism - complications
Hyperlipidemias - complications
Hypertension - complications
Memory
Memory Disorders - etiology
Memory Disorders - psychology
Metabolism
Risk Factors
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Beschreibung
Zusammenfassung:Type 2 diabetes is associated with an increased risk of cognitive dysfunction. These effects seem particularly true for memory functions. This article examines how diabetes and the biological changes that occur with diabetes such as hyperglycemia, changes in insulin concentration, hypertension, and changes in lipid levels might lead to these alterations in cognitive functioning, with an emphasis on the mechanisms leading to changes in memory.
ISSN:1079-5006
1758-535X
DOI:10.1093/gerona/55.5.b228