Influence of Ageing on Vasomotor Responses of Human Epicardial Coronary Arteries

: Vasomotor responses to various agonists were studied on isolated circular segments of human epicardial coronary arteries from three different age groups; 23–38 years, 40–58 years and 63–86 years. Noradrenaline had no or only weak contractile effect on coronary arteries from younger patients but in...

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Veröffentlicht in:	Pharmacology & toxicology 2000-04, Vol.86 (4), p.183-191
Hauptverfasser:	Opgaard, Ole Saetrum, Ytterberg2, Hoa T., Saxena, Pramod R., Edvinsson, Lars
Format:	Artikel
Sprache:	eng
Schlagworte:	15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology Adult Aged Aged, 80 and over Aging Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Calcitonin Gene-Related Peptide - pharmacology Cardiology. Vascular system Cardiomyopathies - physiopathology Coronary Vessels - drug effects Coronary Vessels - physiology Coronary Vessels - physiopathology Dose-Response Relationship, Drug Endothelins - pharmacology Humans In Vitro Techniques Medical sciences Middle Aged Norepinephrine - pharmacology Substance P - pharmacology Vasoactive Intestinal Peptide - pharmacology Vasoconstriction - drug effects Vasoconstrictor Agents - pharmacology Vasodilation - drug effects Vasomotor System - drug effects Vasomotor System - physiology Vasomotor System - physiopathology
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