REST Acts through Multiple Deacetylase Complexes
The RE1 binding silencer protein REST represses neuronal-specific gene expression in nonneuronal cell types. In this issue of Neuron, Ballas et al. show that REST inhibits gene expression via the recruitment of multiple histone deacetylase complexes.
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| Veröffentlicht in: | Neuron 2001-08, Vol.31 (3), p.339-340 |
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| container_end_page | 340 |
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| container_issue | 3 |
| container_start_page | 339 |
| container_title | Neuron |
| container_volume | 31 |
| creator | Griffith, Eric C. Cowan, Christopher W. Greenberg, Michael E. |
| description | The RE1 binding silencer protein REST represses neuronal-specific gene expression in nonneuronal cell types. In this issue of
Neuron, Ballas et al. show that REST inhibits gene expression via the recruitment of multiple histone deacetylase complexes. |
| doi_str_mv | 10.1016/S0896-6273(01)00386-5 |
| format | Article |
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| language | eng |
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| source | MEDLINE; Cell Press Free Archives; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Access via ScienceDirect (Elsevier) |
| subjects | Amidohydrolases - metabolism Animals DNA-Binding Proteins - metabolism Gene Silencing Neurons - physiology Promoter Regions, Genetic Repressor Proteins - metabolism Spinal Cord - physiology Transcription Factors - metabolism Transcription, Genetic Zinc Fingers |
| title | REST Acts through Multiple Deacetylase Complexes |
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