Prenatal evaluation of fetal renal function based on serum beta(2)-microglobulin assessment

The relationship between fetal renal function (FRF) and fetal serum beta(2)-microglobulin (B2MG) was investigated by comparing its value in 112 unaffected fetuses with that of 23 fetuses presenting with urinary tract malformations (UTM). Fetal serum level of B2MG was totally unrelated to gestational...

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Veröffentlicht in:	Prenatal diagnosis 2001-07, Vol.21 (7), p.586-588
Hauptverfasser:	Ciardelli, V, Rizzo, N, Farina, A, Vitarelli, M, Boni, P, Bovicelli, L
Format:	Artikel
Sprache:	eng
Schlagworte:	beta 2-Microglobulin - blood Case-Control Studies Female Fetal Blood Fetal Diseases - blood Fetal Diseases - diagnosis Fetal Diseases - physiopathology Gestational Age Humans Kidney Diseases - blood Kidney Diseases - diagnosis Kidney Diseases - physiopathology Kidney Function Tests Predictive Value of Tests Pregnancy Prenatal Diagnosis - standards Sensitivity and Specificity Urinary Tract - abnormalities
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Zusammenfassung:	The relationship between fetal renal function (FRF) and fetal serum beta(2)-microglobulin (B2MG) was investigated by comparing its value in 112 unaffected fetuses with that of 23 fetuses presenting with urinary tract malformations (UTM). Fetal serum level of B2MG was totally unrelated to gestational age; its value increased in cases of severe impairment of FRF but was similar to controls in all mild uropathies (p
ISSN:	0197-3851