Beneficial effect of prodromal angina pectoris is lost in elderly patients with acute myocardial infarction

Beneficial effect of prodromal angina pectoris is lost in elderly patients with acute myocardial infarction

Background Prodromal angina pectoris occurring shortly before the onset of acute myocardial infarction is associated with a favorable outcome by the mechanism of ischemic preconditioning. Recent experiments have reported that the beneficial effect of ischemic preconditioning are reversed in the aged...

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Veröffentlicht in:The American heart journal 2000-05, Vol.139 (5), p.881-888
Hauptverfasser: Ishihara, Masaharu, Sato, Hikaru, Tateishi, Hironobu, Kawagoe, Takuji, Shimatani, Yuji, Ueda, Kentarou, Noma, Kensuke, Yumoto, Akihisa, Nishioka, Kenji
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Angina Pectoris - diagnosis
Angina Pectoris - mortality
Biological and medical sciences
Cardiology. Vascular system
Coronary Angiography
Coronary heart disease
Female
Heart
Hospital Mortality
Humans
Ischemic Preconditioning
Male
Medical sciences
Middle Aged
Myocardial Infarction - diagnosis
Myocardial Infarction - mortality
Prognosis
Risk Factors
Survival Rate
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Zusammenfassung:Background Prodromal angina pectoris occurring shortly before the onset of acute myocardial infarction is associated with a favorable outcome by the mechanism of ischemic preconditioning. Recent experiments have reported that the beneficial effect of ischemic preconditioning are reversed in the aged heart. Methods We studied 990 patients who underwent coronary angiography within 12 hours after the onset of acute myocardial infarction. Patients were divided into 2 groups: those aged
ISSN:0002-8703
1097-6744
DOI:10.1016/S0002-8703(00)90021-8