The role of resection for patients with renal carcinoma

Metastatic renal cancer is responsive in some cases to immunotherapeutic agents. Indications for nephrectomy in the face of metastatic disease have traditionally included palliation of symptoms caused by the primary tumor, and nephrectomy combined with metastatectomy in patients with resectable meta...

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Veröffentlicht in:	Current oncology reports 2001-09, Vol.3 (5), p.424-432
Hauptverfasser:	Flanigan, R C, Yonover, P M
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Renal Cell - immunology Carcinoma, Renal Cell - secondary Carcinoma, Renal Cell - surgery Combined Modality Therapy Humans Immunotherapy Infarction - immunology Kidney - blood supply Kidney Neoplasms - immunology Kidney Neoplasms - pathology Kidney Neoplasms - surgery Nephrectomy Prognosis
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Beschreibung
Zusammenfassung:	Metastatic renal cancer is responsive in some cases to immunotherapeutic agents. Indications for nephrectomy in the face of metastatic disease have traditionally included palliation of symptoms caused by the primary tumor, and nephrectomy combined with metastatectomy in patients with resectable metastases. Recent findings from a Southwest Oncology Group trial strongly suggest that cytoreductive nephrectomy, combined with immunotherapy, may also result in improved survival in patients with unresectable metastases.
ISSN:	1523-3790 1534-6269
DOI:	10.1007/s11912-001-0029-0