N-p-nitrobenzyloxycarbonyl galactosamine imidate as a glycosyl donor for the efficient synthesis of mucin core-2 analogue

An efficient synthesis of the mucin core-2 analogue 1a was accomplished using N-p-nitrobenzyloxycarbonyl(PNZ)-protected trichloroacetimidate 4 as a novel glycosyl donor.

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Bibliographische Detailangaben
Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2000-04, Vol.10 (8), p.793-795
Hauptverfasser:	WENSHENG LIAO, PISKORZ, C. F, LOCKE, R. D, MATTA, K. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbohydrate Sequence Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides Carbohydrates. Nucleosides and nucleotides Chemistry Exact sciences and technology Galactosamine - analogs & derivatives Galactosamine - chemistry Molecular Sequence Data Mucins - chemical synthesis Mucins - chemistry Nitrobenzenes - chemistry Organic chemistry Preparations and properties
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Beschreibung
Zusammenfassung:	An efficient synthesis of the mucin core-2 analogue 1a was accomplished using N-p-nitrobenzyloxycarbonyl(PNZ)-protected trichloroacetimidate 4 as a novel glycosyl donor.
ISSN:	0960-894X 1464-3405
DOI:	10.1016/S0960-894X(00)00107-4