An Expeditious Approach toward the Total Synthesis of CP-263,114
Assembly of the carbocyclic core of CP-263,114 has been accomplished efficiently and in high yield. Key steps include a phenolic oxidation/intramolecular Diels−Alder sequence, tandem radical cyclization, and the late-stage fragmentation of a densely functionalized isotwistane skeleton.
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| Veröffentlicht in: | Organic letters 2001-08, Vol.3 (16), p.2435-2438 |
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| container_issue | 16 |
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| container_title | Organic letters |
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| creator | Njardarson, Jón T McDonald, Ivar M Spiegel, David A Inoue, Munenori Wood, John L |
| description | Assembly of the carbocyclic core of CP-263,114 has been accomplished efficiently and in high yield. Key steps include a phenolic oxidation/intramolecular Diels−Alder sequence, tandem radical cyclization, and the late-stage fragmentation of a densely functionalized isotwistane skeleton. |
| doi_str_mv | 10.1021/ol015979n |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1523-7060 |
| ispartof | Organic letters, 2001-08, Vol.3 (16), p.2435-2438 |
| issn | 1523-7060 1523-7052 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71057083 |
| source | MEDLINE; ACS Publications |
| subjects | Cyclization Enzyme Inhibitors - chemical synthesis Indicators and Reagents Maleic Anhydrides - chemical synthesis Models, Molecular Oxidation-Reduction |
| title | An Expeditious Approach toward the Total Synthesis of CP-263,114 |
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