The Significance of Mast Cells Associated with Basal Cell Carcinoma

In the stroma of basal cell carcinoma (BCC), the numbers of mast cells are increased, but their significance remains unknown. In a retrospective histological study of 74 cases, we investigated the significance of mast cells related to BCC and the possible relationship between increased numbers of ma...

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Veröffentlicht in:	Journal of dermatology 2001-06, Vol.28 (6), p.312-315
Hauptverfasser:	Erkilic, Suna, Erbagci, Zuelal
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult age Aged Aged, 80 and over basal cell carcinoma Carcinoma, Basal Cell - pathology Female Humans Male mast cells Mast Cells - pathology Middle Aged morpheaform Retrospective Studies Severity of Illness Index sex Skin Neoplasms - pathology
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Zusammenfassung:	In the stroma of basal cell carcinoma (BCC), the numbers of mast cells are increased, but their significance remains unknown. In a retrospective histological study of 74 cases, we investigated the significance of mast cells related to BCC and the possible relationship between increased numbers of mast cells and clinical and histological parameters including the patients' age, sex, subtype of BCC, and severity of peritumoral inflammation. We found a significant increase in peritumoral mast cell numbers over those in uninvolved skin (p
ISSN:	0385-2407 1346-8138
DOI:	10.1111/j.1346-8138.2001.tb00139.x