New Antioxidant and Antimicrobial Ellagic Acid Derivatives from Pteleopsis hylodendron

Abstract Bioassay-guided isolation of two new compounds, 3,4-methylenedioxy-3′-O-methyl-4′-O-glucoside ellagic acid (1) and the pteleoellagic acid derivative (2), from the stem bark of PTELEOPSIS HYLODENDRON is reported along with 3,4-methylenedioxy-3′-O-methyl ellagic acid (3), 3,3′-di-O-methyl ellagic acid (4) and 3,3′,4′-tri-O-methyl ellagic acid (5), which were obtained for the first time from this plant. The structures of these compounds were elucidated with the help of spectroscopic studies. Compounds 1 and 4 were found to have significant antioxidant activity, while compounds 1 - 4 showed antibacterial activity against different pathogenic bacteria.