Confidence bands for comparison of transition probabilities in a Markov chain model

We consider graphs, confidence procedures and tests that can be used to compare transition probabilities in a Markov chain model with intensities specified by a Cox proportional hazard model. Under assumptions of this model, the regression coefficients provide information about the relative risks of...

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Veröffentlicht in:Lifetime data analysis 2000-03, Vol.6 (1), p.5-21
Hauptverfasser: Dabrowska, D M, Ho, W T
Format: Artikel
Sprache:eng
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Zusammenfassung:We consider graphs, confidence procedures and tests that can be used to compare transition probabilities in a Markov chain model with intensities specified by a Cox proportional hazard model. Under assumptions of this model, the regression coefficients provide information about the relative risks of covariates in one-step transitions, however, they cannot in general be used to to assess whether or not the covariates have a beneficial or detrimental effect on the endpoint events. To alleviate this problem, we consider graphical tests based on confidence procedures for a generalized Q-Q plot and for the difference between transition probabilities. The procedures are illustrated using data of the International Bone Marrow Transplant Registry.
ISSN:1380-7870
1572-9249
DOI:10.1023/A:1009681332533