Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases
Pravastatin decreases serum MMP-9 concentration in clinically healthy men. This may reflect reduction of nonsymptomatic chronic arterial inflammation.
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| Veröffentlicht in: | The American journal of cardiology 2001-07, Vol.88 (2), p.173-175 |
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| container_issue | 2 |
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| container_title | The American journal of cardiology |
| container_volume | 88 |
| creator | Kalela, Anne Laaksonen, Reijo Lehtimäki, Terho Koivu, Tommi A. Höyhtyä, Matti Janatuinen, Tuula Pöllänen, Perttu Vesalainen, Risto Saikku, Pekka Knuuti, Juhani Nikkari, Seppo T. |
| description | Pravastatin decreases serum MMP-9 concentration in clinically healthy men. This may reflect reduction of nonsymptomatic chronic arterial inflammation. |
| doi_str_mv | 10.1016/S0002-9149(01)01616-2 |
| format | Article |
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Vitamins</subject><subject>Genotype</subject><subject>Humans</subject><subject>Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology</subject><subject>Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use</subject><subject>Hypercholesterolemia - drug therapy</subject><subject>Hypercholesterolemia - enzymology</subject><subject>Lipids</subject><subject>Male</subject><subject>Matrix Metalloproteinase 9 - blood</subject><subject>Matrix Metalloproteinase 9 - drug effects</subject><subject>Matrix Metalloproteinase 9 - genetics</subject><subject>Medical sciences</subject><subject>Men</subject><subject>Pharmacology. 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| ispartof | The American journal of cardiology, 2001-07, Vol.88 (2), p.173-175 |
| issn | 0002-9149 1879-1913 |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Anticholesteremic Agents - pharmacology Anticholesteremic Agents - therapeutic use Biological and medical sciences Cardiology Cholesterol Double-Blind Method Drug therapy General and cellular metabolism. Vitamins Genotype Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hypercholesterolemia - drug therapy Hypercholesterolemia - enzymology Lipids Male Matrix Metalloproteinase 9 - blood Matrix Metalloproteinase 9 - drug effects Matrix Metalloproteinase 9 - genetics Medical sciences Men Pharmacology. Drug treatments Polymorphism, Genetic Pravastatin - pharmacology Pravastatin - therapeutic use Proteins |
| title | Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases |
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