Abnormal brachial artery flow-mediated vasodilation in young adults with major depression

Depressive illness in patients without traditional risk factors for coronary artery disease is associated with striking abnormalities of endothelial function and elevation of circulating markers of atherosclerosis propensity. Further studies are needed to define the mechanisms that underlie these ob...

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Veröffentlicht in:	The American journal of cardiology 2001-07, Vol.88 (2), p.196-198
Hauptverfasser:	Rajagopalan, Sanjay, Brook, Robert, Rubenfire, Melvyn, Pitt, Elaine, Young, Elizabeth, Pitt, Bertram
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Blood pressure Brachial Artery - physiopathology Cardiology Cardiology. Vascular system Case-Control Studies Chemokine CCL2 - analysis Coronary Disease - epidemiology Coronary heart disease Coronary vessels Depressive Disorder - physiopathology E-Selectin - analysis Endothelium, Vascular - physiopathology Enzyme-Linked Immunosorbent Assay Female Heart Humans Hyperemia - physiopathology Intercellular Adhesion Molecule-1 - analysis Male Medical sciences Mental depression Risk Factors Vascular Cell Adhesion Molecule-1 - analysis Vasodilation - physiology Young adults
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Beschreibung
Zusammenfassung:	Depressive illness in patients without traditional risk factors for coronary artery disease is associated with striking abnormalities of endothelial function and elevation of circulating markers of atherosclerosis propensity. Further studies are needed to define the mechanisms that underlie these observations.
ISSN:	0002-9149 1879-1913
DOI:	10.1016/S0002-9149(01)01623-X