Inhibitory effects of anthraquinones and bianthraquinones on Epstein-Barr virus activation

Short-term in vitro assays for anti-tumor promoters were carried out for several anthraquinones and bianthraquinones, which were isolated from Cassia siamea and derived from cascaroside A. Anthraquinone monomers showed higher anti-tumor promoting activity than that of bianthraquinones.

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Bibliographische Detailangaben
Veröffentlicht in:	Cancer letters 2001-09, Vol.170 (1), p.15-18
Hauptverfasser:	Koyama, Junko, Morita, Izumi, Tagahara, Kiyoshi, Ogata, Masakazu, Mukainaka, Teruo, Tokuda, Harukuni, Nishino, Hoyoku
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anthraquinone anthraquinones Anthraquinones - pharmacology Anti-tumor promoting effect Bianthraquinone bianthraquinones Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens cascaroside A Cassia siamea Cell Line Chemical agents Epstein-Barr virus Epstein-Barr virus activation Herpesvirus 4, Human - drug effects Herpesvirus 4, Human - physiology Medical sciences Tumors Virus Replication - drug effects
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Beschreibung
Zusammenfassung:	Short-term in vitro assays for anti-tumor promoters were carried out for several anthraquinones and bianthraquinones, which were isolated from Cassia siamea and derived from cascaroside A. Anthraquinone monomers showed higher anti-tumor promoting activity than that of bianthraquinones.
ISSN:	0304-3835 1872-7980
DOI:	10.1016/S0304-3835(01)00566-3