Inhibitory Effect of Herbal Medicines on Rotavirus Infectivity
The inhibitory effect of some traditional herbal medicines on the infectivity of rotavirus, which predominanthy occurs in sporadic diarrhea in infants and young children, was investigated. Among the 34 kinds of herbal medicines tested, the fruit of Citrus aurantium had the most potent inhibitory act...
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| Veröffentlicht in: | Biological & pharmaceutical bulletin 2000/03/01, Vol.23(3), pp.356-358 |
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| container_end_page | 358 |
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| container_start_page | 356 |
| container_title | Biological & pharmaceutical bulletin |
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| creator | KIM, Dong-Hyun SONG, Mi-Jeong BAE, Eun-Ah HAN, Myung Joo |
| description | The inhibitory effect of some traditional herbal medicines on the infectivity of rotavirus, which predominanthy occurs in sporadic diarrhea in infants and young children, was investigated. Among the 34 kinds of herbal medicines tested, the fruit of Citrus aurantium had the most potent inhibitory activity on rotavirus infection. The active components of the fruit of Citrus aurantium were neohesperidin and hesperidin. Their 50% inhibitory concentrations were 25 and 10 μM, respectively. |
| doi_str_mv | 10.1248/bpb.23.356 |
| format | Article |
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Among the 34 kinds of herbal medicines tested, the fruit of Citrus aurantium had the most potent inhibitory activity on rotavirus infection. The active components of the fruit of Citrus aurantium were neohesperidin and hesperidin. Their 50% inhibitory concentrations were 25 and 10 μM, respectively.</description><identifier>ISSN: 0918-6158</identifier><identifier>EISSN: 1347-5215</identifier><identifier>DOI: 10.1248/bpb.23.356</identifier><identifier>PMID: 10726895</identifier><language>eng</language><publisher>Tokyo: The Pharmaceutical Society of Japan</publisher><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents ; antirotaviral activity ; Antiviral agents ; Biological and medical sciences ; Citrus aurantium ; General pharmacology ; herbal medicine ; hesperidin ; Medical sciences ; Microbial Sensitivity Tests ; neohesperidin ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. 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Among the 34 kinds of herbal medicines tested, the fruit of Citrus aurantium had the most potent inhibitory activity on rotavirus infection. The active components of the fruit of Citrus aurantium were neohesperidin and hesperidin. Their 50% inhibitory concentrations were 25 and 10 μM, respectively.</description><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>antirotaviral activity</subject><subject>Antiviral agents</subject><subject>Biological and medical sciences</subject><subject>Citrus aurantium</subject><subject>General pharmacology</subject><subject>herbal medicine</subject><subject>hesperidin</subject><subject>Medical sciences</subject><subject>Microbial Sensitivity Tests</subject><subject>neohesperidin</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Phytotherapy</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Extracts - pharmacology</subject><subject>Rotavirus - drug effects</subject><subject>Rotavirus - pathogenicity</subject><subject>Virulence - drug effects</subject><issn>0918-6158</issn><issn>1347-5215</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0E9LHDEYBvBQKnXVXvoBykCLh8Js83eSXARZVl1QBLHnkMQ3NcvszDaZEfbbN9tZrHhJDu8v7xMehL4QPCeUq59u6-aUzZloPqAZYVzWghLxEc2wJqpuiFDH6CTnNcZYYso-oWOCJW2UFjN0seqeo4tDn3bVMgTwQ9WH6gaSs211B0_Rxw5y1XfVQz_Yl5jGXK26vYsvcdidoaNg2wyfD_cp-nW1fFzc1Lf316vF5W3tG6qGmioJUiplPdehoQIrRoAr5Z2inANRTfCSMWF1EM5y6bwmUF4KbYm2wbFTdD7t3ab-zwh5MJuYPbSt7aAfs5FYK8qoLvDbO7jux9SVvxnCeekDN5oU9WNSPvU5Jwhmm-LGpp0h2Ow7NaVTQ5kpnRb89bBydBt4ekOnEgv4fgA2e9uGZDsf83_HiBRcFraY2DoP9je8zm0aom9hH0m0Zv9ip6Okv079s00GOvYXGlqUVg</recordid><startdate>20000301</startdate><enddate>20000301</enddate><creator>KIM, Dong-Hyun</creator><creator>SONG, Mi-Jeong</creator><creator>BAE, Eun-Ah</creator><creator>HAN, Myung Joo</creator><general>The Pharmaceutical Society of Japan</general><general>Maruzen</general><general>Japan Science and Technology Agency</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7QR</scope><scope>7TK</scope><scope>7U9</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20000301</creationdate><title>Inhibitory Effect of Herbal Medicines on Rotavirus Infectivity</title><author>KIM, Dong-Hyun ; SONG, Mi-Jeong ; BAE, Eun-Ah ; HAN, Myung Joo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c628t-287e7788ac49f6250831e488cb8244e186fc7335a9f5ba47bc91e62859a19afb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Antibiotics. 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Drug treatments</topic><topic>Phytotherapy</topic><topic>Plant Extracts - chemistry</topic><topic>Plant Extracts - pharmacology</topic><topic>Rotavirus - drug effects</topic><topic>Rotavirus - pathogenicity</topic><topic>Virulence - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KIM, Dong-Hyun</creatorcontrib><creatorcontrib>SONG, Mi-Jeong</creatorcontrib><creatorcontrib>BAE, Eun-Ah</creatorcontrib><creatorcontrib>HAN, Myung Joo</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Biological & pharmaceutical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KIM, Dong-Hyun</au><au>SONG, Mi-Jeong</au><au>BAE, Eun-Ah</au><au>HAN, Myung Joo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inhibitory Effect of Herbal Medicines on Rotavirus Infectivity</atitle><jtitle>Biological & pharmaceutical bulletin</jtitle><addtitle>Biol Pharm Bull</addtitle><date>2000-03-01</date><risdate>2000</risdate><volume>23</volume><issue>3</issue><spage>356</spage><epage>358</epage><pages>356-358</pages><issn>0918-6158</issn><eissn>1347-5215</eissn><abstract>The inhibitory effect of some traditional herbal medicines on the infectivity of rotavirus, which predominanthy occurs in sporadic diarrhea in infants and young children, was investigated. 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| source | J-STAGE Free; MEDLINE; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Antibiotics. Antiinfectious agents. Antiparasitic agents antirotaviral activity Antiviral agents Biological and medical sciences Citrus aurantium General pharmacology herbal medicine hesperidin Medical sciences Microbial Sensitivity Tests neohesperidin Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - chemistry Plant Extracts - pharmacology Rotavirus - drug effects Rotavirus - pathogenicity Virulence - drug effects |
| title | Inhibitory Effect of Herbal Medicines on Rotavirus Infectivity |
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