Effect of morphine on the number and branching of astrocytes in various regions of rat brain

Effect of morphine on the number and branching of astrocytes in various regions of rat brain

We studied the effects of morphine in high doses on astrocytes in the nucleus accumbens, lateral septum, and caudate nucleus of rat brain. Activation of astrocytes in the nucleus accumbens and lateral septal nucleus was manifested in hyperplasia and elongation of astrocyte processes. In the caudate...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2001-03, Vol.131 (3), p.248-250
Hauptverfasser: Lazriev, I L, Kiknadze, G I, Kutateladze, I I, Nebieridze, M I
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Astrocytes - cytology
Astrocytes - drug effects
Brain - cytology
Brain - drug effects
Dose-Response Relationship, Drug
Immunohistochemistry
Morphine - pharmacology
Rats
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Zusammenfassung:We studied the effects of morphine in high doses on astrocytes in the nucleus accumbens, lateral septum, and caudate nucleus of rat brain. Activation of astrocytes in the nucleus accumbens and lateral septal nucleus was manifested in hyperplasia and elongation of astrocyte processes. In the caudate nucleus, the total length of astrocyte processes and branching of individual astrocytes decreased.
ISSN:0007-4888
1573-8221
DOI:10.1023/A:1017699315355