The characterization of a mouse mutant that displays abnormal mammary gland development

Deficiencies and supernumerary mammary glands in inbred strains of mice have been reported and were postulated to have a genetic basis. Here we describe a naturally occurring mouse mutation named scaramanga that displays abnormal embryonic and postnatal mammary gland development found in the A/J strain of mice. We have performed a genetic analysis of this mutation and have determined that a single autosomal recessive locus appears to be responsible for this trait.