The influence of histopathological diagnosis on the clinical expression of localized Castleman's disease: apropos 2 cases

The localized Castleman's disease (CD) seemingly has a different clinical behaviour depending on whether the pathologic study is consistent with the plasma cell (PC) or with the hyaline-vascular types. We report here two cases of localized CD with associated analytical changes, although only the PC modality was associated with symptoms. Surgery proved effective, and the systemic picture disappeared in both cases, as well as clinical manifestations in the PC variant.