A pendular mechanism for maintenance of the immune memory

A pendular mechanism for maintenance of the immune memory

A possible mechanism for maintaining immune memory, based on idiotypic–anti-idiotypic interactions, is described. It is proposed that pendular dynamic swings in the levels of idiotypic antibodies (Ab1) and anti-idiotypic Ab2 may underlay immune memory. In the terms of the advanced concept, Ab dynami...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Medical hypotheses 2001-02, Vol.56 (2), p.160-162
Hauptverfasser: Seledtsov, V.I., Seledtsova, G.V.
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies, Anti-Idiotypic - immunology
Body Fluids - immunology
Humans
Immunologic Memory
Infant, Newborn
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A possible mechanism for maintaining immune memory, based on idiotypic–anti-idiotypic interactions, is described. It is proposed that pendular dynamic swings in the levels of idiotypic antibodies (Ab1) and anti-idiotypic Ab2 may underlay immune memory. In the terms of the advanced concept, Ab dynamics in the maternal body might also play a significant role in education of the neonatal immune system.
ISSN:0306-9877
1532-2777
DOI:10.1054/mehy.2000.1132