New DRB1 alleles (HLA-DRB11135, DRB11430 and DRB11433) and a confirmatory sequence (DRB11133)

Three new DRB1 alleles (DRB1*1135, DRB1*1430 and DRB1*1433) and a confirmatory sequence (DRB1*1133) have been identified after following up unusual or novel polymerase chain reaction‐restriction fragment length polymorphism (PCR‐RFLP) patterns during routine typing of the DRB1*03,*08,*11,*12,*13 and...

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Veröffentlicht in:Tissue antigens 2000-01, Vol.55 (1), p.89-91
Hauptverfasser: Tréjaut, J., Hobart, D., Kennedy, A., Greville, W.D., Taverniti, A., Dunckley, H.
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Sprache:eng
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Zusammenfassung:Three new DRB1 alleles (DRB1*1135, DRB1*1430 and DRB1*1433) and a confirmatory sequence (DRB1*1133) have been identified after following up unusual or novel polymerase chain reaction‐restriction fragment length polymorphism (PCR‐RFLP) patterns during routine typing of the DRB1*03,*08,*11,*12,*13 and *14 allele groups. Of the new alleles found and described in this paper, two alleles were initially detected by the PCR‐RFLP method which produced unexpected restriction polymorphism (DRB1*1133 and DRB1*1135) while the remaining two were found after following up rare allele typings from this technique (DRB1*1430 and DRB1*1433).
ISSN:0001-2815
1399-0039
DOI:10.1034/j.1399-0039.2000.550120.x