Absence of BAT-26 instability in gastric intestinal metaplasia

BAT‐26 instability, a sensitive marker for the high‐frequency microsatellite instability (MSI‐H) phenotype, was analyzed in samples of gastric cancer and in adjacent intestinal metaplastic mucosae. Although all MSI‐H gastric cancer samples showed BAT‐26 instability, as assessed using 12 dinucleotide...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pathology international 2001-06, Vol.51 (6), p.473-475
Hauptverfasser:	Jin, Zhe, Tamura, Gen, Satoh, Michiko, Meguro, Toru, Miura, Takayuki, Hayashi, Masahiro, Osakabe, Mitsumasa, Ohmura, Kiyonari, Ogata, Shin-ya, Endoh, Yasushi, Motoyama, Teiichi
Format:	Artikel
Sprache:	eng
Schlagworte:	BAT-26 gastric cancer Genetic Markers Humans Intestinal Diseases - genetics Intestinal Diseases - pathology intestinal metaplasia Intestinal Mucosa - pathology Metaplasia - genetics Metaplasia - pathology microsatellite instability Microsatellite Repeats - genetics Precancerous Conditions - genetics Precancerous Conditions - pathology Stomach Neoplasms - genetics Stomach Neoplasms - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	BAT‐26 instability, a sensitive marker for the high‐frequency microsatellite instability (MSI‐H) phenotype, was analyzed in samples of gastric cancer and in adjacent intestinal metaplastic mucosae. Although all MSI‐H gastric cancer samples showed BAT‐26 instability, as assessed using 12 dinucleotide microsatellite markers, BAT‐26 instability was not found in the adjacent intestinal metaplastic mucosa in any of the samples.
ISSN:	1320-5463 1440-1827
DOI:	10.1046/j.1440-1827.2001.01220.x