Modulation of intramacrophage iron metabolism during microbial cell invasion

The mechanisms whereby vertebrate hosts withhold iron from microbial invaders, as well as the methods used in attempts by invaders to capture the growth-essential metal, differ between host extracellular and intracellular environments. This review focuses on procedures employed by host cells and by...

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Veröffentlicht in:	Microbes and Infection 2000, Vol.2 (1), p.85-89
1. Verfasser:	Weinberg, Eugene D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria - growth & development Bacterial Infections - metabolism Bacterial Infections - microbiology Bacteriology Biological and medical sciences Carrier Proteins - metabolism Cation Transport Proteins Fundamental and applied biological sciences. Psychology Humans iron Iron - metabolism macrophages Macrophages - metabolism Membrane Proteins - metabolism Microbiology nitric oxide Nitric Oxide - metabolism Nrampl Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains transferrin receptors
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Zusammenfassung:	The mechanisms whereby vertebrate hosts withhold iron from microbial invaders, as well as the methods used in attempts by invaders to capture the growth-essential metal, differ between host extracellular and intracellular environments. This review focuses on procedures employed by host cells and by invaders, respectively, that alter intramacrophage iron metabolism.
ISSN:	1286-4579 1769-714X
DOI:	10.1016/S1286-4579(00)00281-1